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Shelly, I have not taken Botox, but will tell you what it says in my drug handbook. (These can be purchased at all major book stores and are handy for ANYONE taking pharmaceuticals!) Botox is botulinum toxin type A, primarily used for eye problems according to this book. It is a protein that produces a neuromuscular paralysis by binding to acetylcholine receptors on the motor endplate and that may inhibit the release of acetylcholine from nerve endings. It's onset occurs in 1-2 days after injection. Peak occurs within 1-2 weeks. Effects persist for 2-6 weeks. There is much more, but also very technical, and not pertaining that specific use - the feet. I don't know if this helps any, or is more confusing. It sounds like a kind of nerve blocker. Kathy Sedler [log in to unmask]