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SUBSCRIBE parkinsn Stephen Howell This is a message I posted to the drugs side effects BBS of the health forum on MSN. I am relieved, I was hoping that someone out there knew what I was talking about, having chronic side effects without anyone knowing what they are exactly is quite frightening. I have tried other various drugs but all major tranquillizers can cause parkinsonism to some degree, e.g. I have been prescribed Chlorpromazine, Trifluroperazine, Thioridazine, Pimozide and god knows how many others ( I can only remember their names because of the dreadful reactions I had to them). The problem is that I originally developed a psychotic illness along with depression and in order to control those symptoms I had to be put on some form of major tranquillizer, flupenthixol was the only one they could find which did not produce chronically debilitating side effects as the others (even though they are still pretty bad). I guess you could say that im in a catch 22 situation. I did read something about the drug blocking dopamine receptors in the brain ( or something like that) this can increase muscle tension to a high degree and can also cause a tremor (in severe cases), the others I went on caused a neck spasm similar to dystonia, not nice :-( PS. The psychosis was (according to my Psychiatrist) caused by drug abuse. I experimented with the street drugs Cannabis and LSD about two years ago ironically to celebrate the end of my GCSE exams (as we call them in the UK). I was only 16 and didn't know what I was messing with. The psychotic symptoms seem to have dissappeared but im wondering if the cause of my unpleasant bodily sensations maybe a long term result of the abuse of these drugs and not side effects of my medication. I didn't know what was in the stuff I took and wonder if there could have been a harmful substance in the drugs which made things worse. I did only take LSD once but have been told that it can have long term effects after one dose :-(. All of the above was posted and I was advised to contact the parkinsns list serve group. Regs Stephen