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I guess I should know better than anyone how to explain this, but I really don't know all that much. By your question, I must assume that you don't know what CO is, so don't think me condescending when I tell you. CO is the symbol for the chemical compound formed by one atom of carbon and one atom of oxygen, better known as carbon monoxide. This form of these two elements forms a colorless, ordorless, and extremely toxic gas. It is formed by the imcomplete combustion of fossil fuels, such as patroleum. Which is how poisoning takes place. Most carbon monoxide poisonings occur in homes with faulty furnaces. In other words, the fuel is not being totally "Burnt", for lack of a better word. Most other poisonings are suicide attempts, usually taking place in a garage. Leaving the engine running, and shutting the garage door, unless you have a super clean running engine will normally kill a person in about an hour. Even the experts are not sure exactly how CO affects the brain. They do know that instead of receiving oxygen in its pure form, the brain is forced to begin accepting CO, robbing the body of hemoglobin, or something like that. Anyways, that is where my knowledge ends. Except for the fact, and I guess I probably went through all of that scientific jargon for nothing, that in some cases, as in mine, CO poisoning can cause a Parkinson's like syndrome. Or it may even cause P.D. itself as it did in the case of another member of this list, depending on the duration of exposure. Again, even the most knowledgable scientists still don't know why this poison chooses to attack the dopamine system in some victims, and severe cognitive damage in others, which is a whole other matter altogether. i sincerely hope that you can find a better explanation than this somewhere else. Regards, Jacob Drollinger