In the 'for what it's worth' department Jeff (46/8) and I feel supplements can make an enormous difference with special emphasis on antioxidents. Jeff takes nearly all that you (Ron) do plus others you might want to look into and consider - Garlic, Ginseng, NADH, Selenium, Chromium, B100, Calcium/Magnesium and a good multivitamin (he takes Twin Labs DualTabs) - all seem to help. Plus, Jeff has just added DHEA, Acetyl L-Carnitine and will soon add Sun Chlorella based on results seen in other pd friends. Jeff takes no Sinemet yet - stiffness is still noticable but better than a year ago and his energy and ability to concentrate is 100% better than a year ago. It does take time, Ron for the supplements to fully 'kick in' but hang in there. At Jeff's last neuro visit, she commented that he was 'less Parkinsonian' - not inferring the supplements are a cure but they are helping. Exercise seems to help Jeff immensely too; he has no method, he just tries to do what he enjoys whether it's golf, tennis, handball or walking (daily schedule, kids schedules and weather dictate the choice of the day!). Keep us posted. Best Regards, Lisa Carper >I'm still a novice at PD (about a year) and have some vague hope that >antioxidants will slow the progress of the disease. In terms of >prescription drugs, I'm on 10mg of Eldepryl per day. > >Supplements I have found helpful are: > >Gingko: Prevents drowsiness in afternoon, seems to make me more alert. >Cell Guard: Reduced stiffness and rigidity in my right wrist. > >Anti-oxidants I am taking include: >Lipoic Acid (100mg). >Vitamin E (600 IU) >Vitamin C >CoQ10 >Pyknogenol (sp?) > >I also take KAL Multiples and Anti-Oxidants which are both rich in the >flavanoids etc. I guess that there is no way to tell if the anti-ox's are >working except over long periods of time. My neuro did give a possible nod >of approval for lipoic acid after researching it on Medline. > > Ron Reiner ([log in to unmask]) 49 + 1yr > > --