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aTO Brian in the UK ,, you told a very interesting story about seleg. Eldepryl deprenyl,,,etc. But in my case it sounds like just hearsay , rumors and conjectures. first of all: the u.k. story on early death has not been accepted over here , and neurol. are saying for the most part keep on using it., until more conclusive results are received. I am obviously prejudiced since I've been taking it since its acceptance here 7 or 8 years ago. Naturally I am concerned about expiring but my drs. marvel about the almost unperceptible advance of my PD , specially since I take only eldepryl and 1000 mg vit. E daily. I know it varies from case to case, but fellow PD' ers I see taking all those sinem, par..etc. are doing worst and with lousy side effects. I dont know why drs. rush to prescribe sine. immediately upon diagnosis. I see PD'ERS with very little rigidity or tremors taking heavy doses, which I will not do until i am quite immobilized and incapacitated. sorry for long discourse, just returned from a month cruising the UK, Ireland , Wales and Scotland. didnt do my taxes yet, sunny days are for tennis, five grandkids keep me hopping, working on the INterneet 4-5 hours daily (getting business for my air cargo firm at JFK Airport), writing a column for a local newspaper, i'm getting excited and my left hand is going, but typing stops it, so i bid you adieu. (by the way i listen to bbc, and sometimes call my london office to comment about traffic on the Ml best regards==