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Some months ago, ALAN B suggested that I was taking far too much Carbodpa and suggested I cut it back. It is now five months after my May Pallidotomy and with my neuro's help I have cut back about 40% of CR Parlodel but not Sinemet and Permax. I just replaced my 25/100 with 10/100 and want to hear from other how or if they experienced any differences. I take 9 a day in OJ over a 16 hour period. Joyce