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>The question about an "off day" came just after I'd experienced the same >thing (though not on the same day, so we can't blame the stars or the >weather). Yesterday I was locked into rigidity no matter what I did. >Intake of food didn't seem to be a factor. I wondered about the pills >themselves -- is it possible that Sinemet can deteriorate significantly >if, for instance, exposed to heat in a car -- or to cold, for that matter? Interesting that this topic should come up. I have been wondering exactly the same thing. Lately the rigidity has been so long lasting I wondered if it could be possible that I'd gotten a 'bad' batch of sinemet. Currently I 'm taking liquid sinemet and I also wonder if the amount of ascorbic acid in the mixture has anything to do with the absorbability of it. I know that one day I was beside myself with frustration by dinner time, I was basically immobile - I had guzzled most of the litre of 'meds' by then in an effort to unlock my joints. For some strange reason, someone looked into the coffee grinder and asked why there was blue powder in it - it seems I'd ground the sinemet in the morning , made up the oj, but forgot to mix the two. I'd gone all day on almost a litre of plain oj, 1 CR and umpteen permax. No wonder I couldn't move! Needless to say I haven't done that since, but lately I'm beginning to wonder what else I may be doing wrong. Last night we went out for dinner and I had lamb. It was delicious and I ate much more protein than normal. I know that last night's zombie state was due to the protein consumed, but I'm wondering what else might be contributing. Any suggestions would be welcome. Lynda