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Margaret Tuchman wrote: <<<What do you think of this idea of "sustained, unresolved stress" and/or "chronic, unresolved conflict." There is a1so a 1989 study by Eatough, Kempster, Lees, & Stern which found that, compared with controls, Parkinson patients were more inflexible AND HAD A SIGNIFICANTLY HIGHER INCIDENCE OF ADVERSE CHILDHOOD LIFE EVENTS." Any thoughts?? Let's resolve that we check-in, on a regular basis, with our inner selves and ask "how're you doin'?">>> The psychologists find psychological "causes" (correlations, actually) because they look for them. However, as an amateur know-it-all, my thinking on the effects of stress includes the possibility that neurodegeneration is natural. Sooner or later we die. The neuro-generation of each of us is evolved post-conception, further evolved in babyhood, then childhood, and continues to evolve individually until the individual is killed accidentally, injured significantly, or becomes "tired of living". The label, depressed, becomes obvious to all who look at someone who is withdrawn, alone, has low self-esteem, enjoys none of what little s/he does, ... Life for those with human consciousness is different from less-cognitive species in that we notice eventually that we are the "captains of our ship" or "master of my fate". If we are not feeling recipients of parental love and caring at the start - sufficient to our needs - received when needed - and grow in cognitive terms/abstract, we will have low social skill, self-esteem, confidence .... which will be harder to change as we evolve our personality. Learning to care for self and others is imperative. Loving is caring for self and others. Our uniqueness in abstracting and thinking symbolically and verbally and learning what has been learned by the whole of our species if we choose to study the authors of books and other media recording our history. As long as we are interested in continuing, we will live. It is necessary to sustain the psyche as well as the substrate of the psyche - id est, the body with the homo sapiens mind. If one introspects and does not find s/he loves (cares for) both mental and physical self, there is need to improve one's choices so that one likes (applauds, feels good about) one's self and his/her care of self. Knowing one-self is necessary to choosing interesting and rewarding activity. These will keep one alive and spunky. Despair will deplete one's brain of the messengers that keep our cells alive - then, it dies cell by cell. Perhaps our fear of dying is the underlying reason that so much of our resources are expended to prolong the inevitable a short while. George L. Bousliman wrote: <<All four of the characterics describe yours truly: 1. neurotic/introverted personality 2. sustained, unresolved stress 3. chronic, unresolved conflict 4. major adverse childhood life events. The "cure" for me and perhaps for others may well lie not in drugs or surgery, but rather in something a good deal more lasting and profound i.e., in the spirit.>>> Yes, if one wants to die, his spirit seeks relief. Requiescat in pace. (translated: Rest in peace, but the thought might have been "death is better than living with a decrepit body"). ron 1936, dz PD 1984 Ridgecrest, California Ronald F. Vetter <[log in to unmask]> http://www.ridgecrest.ca.us/~rfvetter/rcpdsg.html/ (Parkinson group) http://www.ridgecrest.ca.us/~rfvetter/