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t L for it! Like you I sometimes wondered why I took the Sinemet but now know when a dose is due. Instead of feeling "off" I realise that I am quite unable to open my eyes to see this wretched video screen. So I suppose that that is how I register being "off". If I do manage to open my eyes and if I get up then I shall probably lose my balance and fall over more readily. It wasn't so easy recognising the "off" signals in the early days. But they were there all right. A pronounced tingling sensation in my left forearm was most useful in finding the minimum dose of Sinemet. Does anybody else have "off" and "on" recognition problems? JACK TIBBS [log in to unmask]