Dear Regina--welcome, and hope you will find things here to help your sister. General questions would be:is she seeing a neuro who understands PD? If she is so depressed, is she on any antidepressant? Does she have a CG living with/close by who can help monitor these things and others? How far away geographically are you? Would you or another CG like to join the CARE list? <[log in to unmask] > SUB CARE (your first and last names) Stay connected! Camilla Flintermann,CG for Peter, 78/7, Oxford,OH