Allan.... I take about 1/2 the pre-surgery dosage of Sinamet, which is all I've ever taken, excepting for 1/2 of a 20 mg. Paxil, (the latter of which has been added since the surgery). There are occasional days when I might take an additional 1/2 Sinemet late in the evening if I feel the need. But on the average day, I take a 1/2 a Sinemet 25/250 about noon, a Sinemet CR 50/200 about 1 hour later, the two of which seems to carry me very well till I take another 1/2 Sinemet 25/250 about 6 p.m., and then 1/2 a Sinemet 25/250 at about 9 p.m. The only other thing I take daily is between 800 and 1200 ICUs of vitamin E daily for toe/leg cramping prevention (works quite well for me), and I wear an estrogen patch for replacement of estrogen (Errrrr.... YOU won't have to consider taking THAT!) <grin> Dr. Iacono believes the pallidotomy as he performs it, will provide lifetime PD symptomatic relief. I'm inclined to believe that based upon my own observations. However, I never forget that in THIS battle, my opponant is VERY devious, and exceptionlly persistant. So frankly, m'dear, I'd say this is ONE thing in life that each of us won't know till we're wearing our respective halos and wings and are floating around in the heavens. At THAT time, we'll be able to take stock of the "Lifetime guarantee." However, future pallidotomy recipients will benefit from what information WE will have provided at the time of our ascension On High <GAWD... I'm waxing lyrical and talking about CROAKING, fer goodness sake!> (grin), as we'll have answered that question. And HEY... maybe by THAT time, no one will even HAVE PD!! Maybe there'll be a "cure," or a vaccine, or.... or...... (Clap if you want Tinkerbell to live!) <do you still believe in the Tooth Fairy?> (SHUDDUP, BARBIE!) Barb Mallut, [log in to unmask] ---------- From: PARKINSN: Parkinson's Disease - Information Exchange Network on behalf of Allan Schumann Sent: Sunday, October 13, 1996 9:37 AM To: Multiple recipients of list PARKINSN Subject: Re: effects of the Pallidotomy,if any. If anyone out there has had a Pallidotomy Thank you Barbara for your response. I appreciate your info and good sense of humor. It's good to hear that your operation was successful. Do you still take the same doses of medication that you took before surgery. What indictationdie Iocono give you as to the expectant duration of the good effects. Did anyone tell you how long it would last? I have heard 5 - 10 years. Then what? thanks, Allan