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Joyce Tames wrote: >> In particular, Im confused at the many responses all quoting difference > daily maximums of B6. It seems that there is concensus on taking not more > than the RDA which seems to be about 25 mg. Joyce, I am in Texas and away from my files, so cannot give a complete answer at this time, but will do my best working from memory. Back before the levodopa/carbidopa combination, B6 seriously interfered with levodopa, and it was advised never to take B6 supplements, or foods high in B6. When carbidopa was added, it removed the interference, and the B6 restriction no longer applied. Your regime is quite high in B vitamins, but ordinarily I would not think it would be a problem. My first guess, and it's only speculation, is that the accident and operations rather than the B vitamins caused a setback resulting in tremor, particularly as your husband sees gradual improvement. Is your tremor in the hand/arm on which the operations were performed? Also, I would not discount the effects of stress; the accident, the resulting operations, and the adaptation you have endured are all productive of great stress, and could cause or contribute to many long-lasting effects, such as tremor. You note you take the vitamins on alternate days; B vitamins are not stored in the body, excess is removed via the urine. Do you notice any difference on the days you don't take B vitamins? Cutting back, as you plan to do, should be a good experiment. I'd allow more than a week, though; at least two or three weeks. There are many possible factors that could cause fluctuations and/or setbacks (such as medications, anesthetics, etc. used during your wrist operations, not to speak of the stress you have been under) particularly if the tremor is in the hand on which operations were performed. I'd also mention this to your doctors; I realize your neurologist was not very helpful regarding the vitamin regime, but I'd bring it up anyway. And your other physicians may have some additional input. My very best regards, Kathrynne -- Kathrynne Holden, MS, RD Editor-in-Chief, "Spotlight on Food--nutrition news for people 60-plus" Tel: 970-493-6532 Fax: 970-493-6538 http://www.fortnet.org/~fivstar You may wish to contact: Better Business Bureau of the Mountain States, < [log in to unmask]> for further information.