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Greetings Steven, I'm sorry you have chosen to express your sentiments regarding NADH in this fashion. While I don't wish to engage in an ongoing 'debate' on the merits of NADH in pd, I would hope that the readers will not stop at your message (particularly as your signature includes 'PhD'). You are quite correct that the mainstream medical community in the U.S. has not recognized NADH however studies are not 100% negative on the efficacy of NADH for pd. I strongly feel that the validity of someone with pd using NADH is highly individual and subjective particularly since there are no apparent side effects. Our (Jeff's 46/8 and my) own knowledge both first and second hand of NADH suggests it absolutely does no harm and in Jeff's case and many others', NADH does provide at least some degree of relief from lack of energy and tremor. If for no other reason than the lack of energy, NADH has great value. Before Jeff started on NADH the tiredness was virutally 'hynotic'; he could hardly stay awake for more than an hour or two at a time. What kind of quality of life is that for a 46 yr old man with a 12 yr old daughter and a 9 yr old son? Fatigue is very much a main sympton of pd so I don't see how the line is so clearly drawn that NADH is a 'waste of time' for pd. I hope in the future we can share our opinions with an even hand and that we all come to appreciate anecdotal information on issues of alternative medicine, prayer/meditation, vitamins, herbs and so on. I readily admit that I am not the one with pd and I also readily admit that I cannot begin to convince Jeff to give up NADH because it's a 'waste of time' and 'useless'. I would agree that NADH is not without controversy; however, many mainstream medications have some degree of controversy in certain situations. I'm sure NADH is not for everyone. I hope everyone will decide for themselves (on NADH) based on their degree of pd, the symptoms they have, their quality of life and so on. Respectfully, Lisa Carper At 09:37 PM 10/26/96 -0400, you wrote: > Neurological studies have shown that there is no good evidence that NADH or DEAE have any use in PD. Fortunately they do not appear to be toxic, >although therer was a recvent message in the PD Digest suggesting that NADH >may produce limited toxic efects. > > Therefore, it is a waste of time collecting the information desired. >At best these drugs are useless. > > Steven [log in to unmask] >Steven E. Mayer, Ph.D. > >