There has been alot of "chat" lately about carbidopa and the effects of having too much. Can anyone tell me what the symptoms of this? I am taking 51/2 to 6 Sinemet 25/100 per day and having lots of problems with dyskenesia and on and off times. Could a reduction in the carbidopa have a positive effect? I am wondering if I should ask my neruo to chang to 10/100 pills instead. Any insight is appreciated. Marty Rose [log in to unmask]