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Marty, I think everyone has just about covered the subject, but do seek help for depression. For years I tried to convince my mom(the caregiver) that she and my dad with PD that they were both depressed. His neuro is also a psychiatrist, so she finally trusted his judgement and tried Prozac for them both. They both have more zest for life and sleep much better. It helped so much and neither have trouble taking it with other meds and they each take many! I agree with Barbara about being cautious about the natural stuff that is really a multilevel marketing scheme which promises miracles. I do believe some natural preparations have merit, but people are taking advantage of ill people in search of a cure. Just be careful. Gail Post Honolulu, HI