This question is for any one doing research in pharmaceuticals. I have noticed that my husband's PD symptoms are decreased substantially after he takes Lopressor (prescribed for hypertension). Infact, Lopressor in combination with Sinemet seems to increase the toxic symptoms of the latter to the point where he has had to cut his Lopressor dose when he takes his 5 p.m. Sinemet (I monitor his BP BTW, and it has remained at safe levels). I know that Beta-blockers are used in cases of non-PD tremor, but I'm wondering if any research has been done to determine whether Lopressor and similar beta-blockers are dopamine agonists. There is nothing that I can find in the literature in this regard. ---- Thank you Mary Ann