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Hello Everyone !! I am curious about tremors. It seems that tremors often do not respond to the Eldepryl and Sinemet regime. I have tried different doses of Sinemet and Sinemet CR, no noticeable change in tremor. I do feel better, less inner trembling, and I do sleep better since taking Sinemet. Also, stiffness in right tremor arm is better. Tremor has progressed in 1 year from right foot to right hand. Not able to write much, especially at work under stress. Would really appreciate any input from fellow PWP's with tremor. I will try Amantadine(Symmetrel) next and then Permax. Thank you ! Barbara Jensen 48, PD diagnosed about 2 yrs ago. First noticeable symptom about 5 years ago. -- Barbara Jensen [log in to unmask]