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I was glad to read of how outside stimuli set off tremors for some of us PWPs. I'm 65, dx 7 years and long-time user of Sinemet CR 50-200; 5 times daily, Parlodel, 4 daily, and eldyprenl, one daily. Currently, we are trying to cut back on the Sinemet, feeling that the high dosages are causing some extreme tremors in both legs and the right arm. This is not so easy a matter to decide, since under-medication has approximately the same effect. But just in the last three to six months I have noticed tremors being set off by the mildest air current from fan or air-conditioner -- a necessity of life here in Central Florida. My feet, already painful from dry, rough skin around the toes (from Parkinson's, I'm told), have become extraordinarily sensitive to cold air. Sox , followed by thermal sox, shoes, and a thick blanket (or air-tight plastic bags) often seems to be the only way to stop the pain. I find, too, that the slightest stress is likely to wipe me out for a day -- taking plastic bottles and newspapers to the recycling center, routine bank routines, dealing with a restaurant meal, etc. This is the more annoying because I have always been the unflappable clear head, to whom colleagues and family turned to in time of crisis. A single Xanax tablet is of some possible help, but still I lose enormous productivity. Would appreciate any shared experiences. Bob Bishop [log in to unmask]