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On Sun 10 Nov, Arthur Stienstra wrote: > I would like any information about the use of Apormorphine for Parkinsons and > Pain related to Parkinsons especially with the use of levadopa (Sinemet) > > AStiens497@AOL COM(Arthur Stienstra) > > Hello Arthur, You ask about Apomorphine for PD, and Pain related to PD, which suggests that you are thinking of Apomorphine as a pain-killer, which it is definitely not. I don't know enough Chemistry to understand what the relationship is between Morphine and Apomorphine, but prior to its being found (by accident I believe) to be useful in controlling PD, it was used as an emetic - That is, to make you throw up!!. PWPs wishing to use Apomorphine have to take a course of medication to suppress the tendency , before using Apomorphine. The chief advantage of Apomorphine is that, because it is administered by injection (Not into a vein) - normally into a muscle on the arms or legs- it takes effect in 5 to 10 minutes, and so can be used to fill in the gap if you miss the time for a Sinemet tablet, for instance. However the duration of effectiveness of each injection is only of the order of 30 minutes, so unless you want to look like a walking pin-cushion, it is really of most use ase a bridge for the occasional unexpected OFF condition. I am curious about your reference to pain and levodopa. I have never had reason to link the two - could you explain? Regards -- Brian Collins <[log in to unmask]>