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I read Dorothy your letter and she wants to know what you meant by the
mortality rate by taking the Eldepryl and Sinemet together.

Also, is it normal to take the Eldepryl with the Sinemt or only one at a time?
What are your dietary habits/restrictions while taking Sinemet, if you can
only take so much protein, knocking out the wine and cheese, red meat etc?

I am not concerned about this group, I was only telling why my father in law
has such a problem with it.  Like you I have been hanging around for awhile
and recognize several names, yours & Barb's for starters.  i agree that
there is no way that anyone could set up a system that anyone could get
passed, if you did it would be too much of a hassle to join and people also
might consider it an invasion of privacy if you were to ask for proof that
they have PD or are taking care of one. Bob is naturally a suspicious
person.  So far I don't have any reason to mistrust the people on this
group.  I did not mean it as an insult to anyone on this group, I was only
voicing my frustrations with him while trying to share information I got off
the group.

the neurologist had told her to start the Sinemet while taking the Eldepryl.
When Dorothy was so sick she was told 2 different things, first by the nurse
who told her to go off the Eldepryl and just take the Sinemet, then by the
neurologist who told her to just go off the Sinemet and back to just the
Eldepryl.  As I said neither one knew the other had called.  Was the nurse
right in the fact that Dorothy needed to go totally off the Eldepryl to
start taking the Sinemet or is it common to take both at the same time?
Her neurologist now no longer wants to try her on it.  I guess she thinks
that Dorothy is satisfied with the Eldepryl.  She isn't but she is now very
scared of taking the Sinemt.
And the neuro only wants to see her once a year, so the neurologist doesn't
worry about it too much obviously.  I wonder how many times she would want
to see Dorothy if she was covered with health insurance and not just
medicaid and medicare.

I agree that the smaller dosages would be better as does her daughter whose
Idea it was to begin with. Thanks to your comments and others that I have
read to her, she is now considering it again.  I believe what you had
suggested was exactly the same thing as Dorothy's daughter had.

I will try tind out about this Madopar drug also.

Thanks for the advice about the orange juice.

Laurie




Very few neurologists now believe
>the MPTP theory, and folowing a recent scare about increased mortality rate
>of people taking levodopa and eldepryl, there has been quite a large movemwnt
>away from eldepryl. Incidentally, Eldepryl does help to slow down the rate
>of degeneration of Dopamine in the brain, and in that way could provide a

>In the general case, careful introduction over a period of 2 weeks or so,
>starting with VERY small doses, and gradually increasing up to the
>recommended dose would be expected to overcome the nausea. I would suggest
>that you try Dorothy on that, starting with small fractions of a  tablet.
>NOTE Do NOT use the Sinemet CRs for this job, use the straight Sinemet tablet
>which contains  100 mg levodopa, 25 mg Carbidopa .
>
enserazide- instead of Carbidopa - to mix with the
>levodopa. This might cause less nausea. - It is worth a try. In all functional
>aspects, madopar is interchangeable with Sinemet.
>
>