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Ralph.... (In the "For what it's worth category") Prior to my 20/24/94 pallidotomy, Dr. Robt. Iacono of Loma Linda University's Movement Disorder Team had me try Periactin (also an old antihistamine like Benadryl) after I had no response from the latter. Not only did the Periactin work well as an anti-tremor drug, but it sure made me sleep at nite!! AND during the morning. AND the afternoon. AND the evening! <grin> I started taking 1/2 a pill instead of a whole one and fortunately, the tremor still was tamed, and drowsiness DID stop after a few days. Barb Mallut [log in to unmask] ---------- From: PARKINSN: Parkinson's Disease - Information Exchange Network on behalf of Ralph Reichert Sent: Wednesday, November 20, 1996 10:17 AM To: Multiple recipients of list PARKINSN Subject: DIPHENHYDRAMINE (BENADRYL) FOR PD ? DIPHENHYDRAMINE IS LISTED AS AN OLD ANTI-PARKINSON DRUG, FOR IT'S ANTICHOLINERGIC ACTION AGAINST TREMOR. HAS ANYONE HAD ANY SUSTAINED BENEFIT FROM BENADRYL? ANY EXPERIENCE WITH THIS DRUG FOR PD? I"LL BE GRATEFUL FOR REPLIES. RALPH