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>Benedryl ( dyphendramine hydrochloride) ointment, oral capsule, >injectable >...is an antihistamine with anticholinergic (drying) and sedative side >effects. >It is used for allergic conditions, in motion sickness, as a sedative, and >in >parkinsonism. Can be sold over the counter ( drug store), BUT should be used >with >considerable caution as there are many possible adverse side effects. >>From the PDR >[log in to unmask] (Mary Manfredi) > Mary, Thank you for this information. My Allergist & also my Pulmonary Doctor will not prescribe Benedryl for anyone, ( you can only buy up to a certain MG over the counter, from there on you need a prescription). I would have to have at LEAST 150 MG to knock what I have now. They both claim it is notoriously known to cause Depression---something a PD patient doesn't need. Thanks to all who posted about Asthma & Allergies. I was born with allergies, my Mother got hay fever for the first time in August & I was born that October. I never had a chance!!! I use inhaled Steriods for my lungs & another inhaler for my nose & use Provental in my Nebulizer. If my Asthma gets bad enough & the Pulmonary Doctor has to give me an Asthma treatment, I have seizures, the good old jacksonian kind! It scared my Allergist so badly he sent me to the Pulmonary Doctor. It was several years before my Asthma got so bad I needed help & then I got to scare the Pulmonary Doctor also!!!! Come to think of it, it really doesn't do much for me either!! Since I never had this problem(seizures) until after diagnosis with PD I don't know, but I'm inclined to believe it must be the PD, which makes it worse. Also, like Barb, Tegretol almost killed me. I was on a slowly increased dosage for 2 weeks. Before I was on a full dose, I broke out in a rash & my skin all peeled off ,& I retained my urine for 16 hours, couldn't walk at all, or get out of bed for 3 days. 1-50 mg. of Mysolin (?) put me in the hospital for 3 days. I had a new Neurologist then (my second) & when he came to the hospital he said "I can't believe this----this is a childs dosage" "Thank God," I said," Or my DH would be planning a funeral"!!!! Now if anyone mentions "Trycyclic" to me I head for the door The moral of this story is---even a childs dosage can kill you if you are allergic to it. PLEASE take a fools advice & be very careful when starting a new medication!!!!! I'm going to look Rondec-TR up in the PDR & discuss it with my Pulmonary Doctor--for now I'm on Cortisone & will get cleared up just in time for the Christmas tree to be put up at the library. Only this time there will be 16 of us sneezing & coughing. Since its such a low percentage of us that are allergic to the Christmas tree, we get to suffer. I'm thinking of practicing Black Magic with a doll & pins!!!!! See there---I have a Dr. Jekyll & Mr. Hyde personality too!!!! As Ever, Marjorie Moorefield just another librarian (with PD)