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Dear Listmembers, I have been a member of this list for 3 years (I think) and have been following the debate on exercise and Parkinson's with great interest! In the last post or two there was discussion concerning the effects of exercise on L-Dopa utilization in the brain and blood stream/muscle metabolism and I have a few articles on this. Here are some citations for those interested in learning more: Carter et al. (1992). The effect of exercise on levodopa absorptition. Neurology, 42, 2042-2045 Goetz et al. (1993). Blood levodopa levels and unified PD rating scale function: With and without exercise. Neurology, 43, 1040-1042. Burleigh et al. (1995). Step initiation in PD: influence of levodopa and external sensory triggers. Brain Hope this sparks some more debate on this very important and controversial topic. Mark Alexander Hirsch, Ph.D. Johns Hopkins University School of Medicine