Hello all Suraiya is not doing very well these days. She is experiencing severe on/offs and is depressed quite often. She also has had hallucinations at times, hearing voices. She has tried to contact her neuro, even written letters... he has not replied. She had had a meeting with him at the end of this past Summer and recommended that she try Tolcapone which will be available sometime next year. He told her that the sinemet was probably not working optimally. She is getting frustrated and anxious. Last year, he recommended she look into having a pallidotomy, but things seemed a bit more positive at the time and she was worried about the risks so she decided to stay with her present regime (at that time). She is now considering pallidotomy as an option again. She will be meeting with a surgeon sometime in the next few weeks. She has been reading up on pallidotomy and making a list of issues for herself. Can anyone offer any issues or question to look into or ask the surgeon? We are trying to be thorough (perhaps too thorough), but we don't want to overlook anything. In the same note, we live in Montreal, Canada and does anyone know the reputable hospitals for pallidotomies. I am not sure of the health insurance issues, but we are looking into it. Thank you in advance. Deanna