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Dick Swindler wrote:
>
> The latest issue (Jan. '97) of Discover Magazine has the latest I've read on
> the issue of smoking and Parkinson's disease.  The quote is short, so I'll
> include it all here:
>
> This is Your Brain on Smoke (title).  Over the past few years, several
> studies have found that people who smoke have about half the risk that
> nonsmokers have of developing Parkinson's disease.  Last February researchers
> reported a possible reason for this strange link:  an enzyme called monoamine
> oxidase B (MAO B).  MAO B is one of the enzymes involved in breaking down the
> neurotransmitter dopamine, which the brain uses when it creates and controls
> movement.  Because people with Parkinson's have unusually low levels of
> dopamine, they suffer from uncontrollable tremors, rigid muscles, and
> difficulty walking and talking.
>      Chemist Joanna Fowler and her colleagues at Brookhaven National
> Laboratory in Upton, New York, PET-scanned the brains of eight smokers, eight
> non-smokers, and four former smokers.  They found that MAO B levels in the
> smokers' brains were 40 percent lower than in the other two groups.  If you
> have less MAO B, the researchers speculate, then you"ll have more available
> dopamine and be less prone to Parkinson's--indeed, some of the best drugs
> used against the disease work by inhibiting MAO B.  What's the ingredient in
> cigarette smoke that does the job?  The researchers only know that it's not
> nicotine.
>
> Thought everyone might be interested in this.       Margie Swindler
>    Lawrence, Ks

Hy!

IMHO the sampling universe of only 8 seems quite low...to be conclusive.


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