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Katherine Brennan-- I believe that Vicodin is an opiate, and therefore not good for PWPs. Any opiates apparently compete with the PD meds for the dopamine receptors. If her doc thinks Vicodin may be a factor, he/she may be right...another possibility to consider is disorientation because of move to NH and strange surroundings. This can be hard on any elderly person, and the stress can aggravate PD symptoms. (This issometimes called "Sundown S yndrome" as it can be worse at night. You might ask about these things. Hope something comes to her rescue soon. Camilla Flintermann,CG for Peter,78/7,Ohio