" From: Camilla Flintermann <[log in to unmask]>
" Subject: Forbidden Drugs
" To: Edwin Partridge <[log in to unmask]>
" In-Reply-To: Message of Sun, 29 Dec 1996 18:14:00 -0500 from
" <[log in to unmask]>
" Allan Netick-- glad you have the drug list - - - - -
" Since you're not on Eldepryl, you can have Demerol if necessary
Please, though, let me recommend extreme caution with regard to Demerol,
even without Eldepryl. Personally, I would not allow it! The following
messages were exchanged on prodigy some time ago with respect to this.
Board: MEDICAL SUPPORT BB
Topic: NEUROLOGICAL
Subject: PD-DEMEROL
To: MXWW92A BEV STEWARD Date: 01/06
From: WKSP90A EDWIN PARTRIDGE Time: 7:31 PM
Hi Bev -- I just received your package on planning for
hospitalization. I noticed with interest that you had added
Demerol to the APDA's list of drugs that are contraindicated
with Parkinson's Disease. I am curious about your reason for
doing this.
I have read that Demerol is related to MPTP, the substance
that afflicted the Californian addicts with parkinsonian
symptoms. I have refused since I learned about this to allow
Demerol to be used as a pain killer.
About three years ago, after a traumatic hernia operation,
Demerol was used on me as a pain killer. It was not long
after that I was diagnosed with Parkinson's Disease, along
with a number of other health problems that had developed. I
asked, why are all these things happening to me? The
neurologist said that Parkinson's Disease frequently
developed after an auto accident or other trauma, and that
probably the trauma of the hernia operation had triggered my
Parkinson's disease.
When you think about it, it's after an operation, or auto
accident, or other trauma, that they give you Demerol as a
pain killer. Could it be that it is the Demerol that causes
or aggravates the parkinsonian conditions?
Maybe not, but why take the risk!
Thanks again for sending me the package. That is very
useful.
Regards, Ed
Board: MEDICAL SUPPORT BB
Topic: NEUROLOGICAL
Subject: PD-DEMEROL
To: WKSP90A EDWIN PARTRIDGE Date: 01/06
From: MXWW92A BEV STEWARD Time: 8:55 PM
In March 1985 I read in the New England Journal of Med. a
letter to the Editor by Abraham N.Lieberman, MD and PD
neurologist, about a patient he had that developed severe
reversible Parkinson's which the doctor attributed to the
use of Meperidine or Demerol. He then concluded that it was
possible that some of the transient worsening that patients
with PD experience after surgery may be due to use of this
medication for post-operative pain.
Because I had noted many cases of post-operative relapses in
Parkinsonians I decided to avoid this drug. Then in 1989,
since Eldepryl (MAO inhibitor) came on the market, Demerol
has definitely been declared a "no-no" in combination with
eldepryl. The PDR says: "Therapeutic doses of meperidine
have occasionally fatal reactions in patients who have
received such agents (MAOs) within 14 days." So I feel that
it is not worth taking any chances. especially when there
are other drugs that will do the pain relieving just as
well.
Bev
[log in to unmask]
* SLMR 2.1a * McLean Virginia USA Tue 12-31-96 6:43 pm
---
* KMail 3.00
