On December 30, Brenda CHALLINGSWORTH posted a message asking for help about SINEMET CR. My answer was : "I also had a bumpy first experience with SINEMET, but I am quite reluctant to give you any kind of advice, because I think the responsibility and the risk have to be taken by a doctor. Doctors may be wrong, or away for vacations, but medical diagnosis and prescription are part of their job. PD patients or caregivers, cannot take into account such things as side effects, interaction between drugs, etc..." Other answers came up in the following days, talking freely and openly about doctors, medical treatment, giving advice based on personal experience. I was quite surprised, if not shocked, until I found out an explanation : there must be a cultural difference between two groups of countries, one including the US and another one including France, about the way we look at the doctor-patient relationship. You seem to have a priori limited confidence in your doctors, while we have a lot of a priori respect for ours. I am not trying to guess which is right or wrong : the truth is probably somewhere betwen the two extremes. Doctors are neither sorcerers nor charlatans. They know PD in general, and they cannot know my PD as well as I do. I know a lot about my PD, but I cannot know PD in general as well as doctors. Since 85% of the subscribers to this list are American, I will apply the proverb "in Rome, do as Romans do" and do my best to help other subscribers. By the way, there is another cultural difference between USA and France. You seem to look up at your lawyers as we look up at our doctors, and vice-versa. Should we consider posting some sort of individual or collective disclaimer ? I do hope I am not frustrating nor irritating anyone, and if I do, I apologize in advance Bernard JOLY [log in to unmask]