Ralph/Karen You wrote: > My Mother is a longtime pd patient. She has a lot of trouble getting > comfortable during the periods when she shakes. She seems to be in > pain, and gets very agitated. Her doctor says he has never seen this > before. He knows she is going to shake at times, the medication just > doesn't control it anymore, but she shouldn't be so uncomfortable. > > Do other patients have this problem? If so, what can we do to help? > It sounds to me as if your mother is experiencing the dyskinesia associated with long term exposure to levadopa. I can speak from personal experience in confiming that this can be extremly painfull. Ask your doctor to look at the problem again from the viewpoint of to much medication. Some PWP find that vitamin C helps reduce the dyskinesia and by extension the pain and discomfort. hope this is some help. Dennis Dennis Greene [log in to unmask]