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Martha, I share your concern about drugs used during surgery. The best bet is to find out in advance what drugs will be used for your husband before, during, and after his surgery; then check with your neuro about their safety. When I was taking eldepryl and needed surgery, I had a hard time convincing my surgeon not to give me demerol. I finally had to have the neurologist call him to tell him it was dangerous. That convinced me that we need to take control of our own bodies; the ignorance about pd I've encountered among doctors is appalling. I'm about the same size as your husband and routinely warn doctors to give me half the medication everyone else gets. That usually works for me. Stil, a doctor recently told me to take an aleve tablet after every meal. I double checked with my pharmacist, who verified my concern that I would be tremendously overdosed if I did. I question everything anymore. Godo luck. Pat Schark pine`