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Aan 10-01-97 1:22, in bericht <[log in to unmask]>, "Charles T. Meyer" <[log in to unmask]> schreef: > Marge, > > Your logic is correct but the datas to my knowledge doeesn't support > it. I as a psychiatrist have never known a PD patient with > Schizophrenia but I believe it can happen. > > There are different arreas of the brain involved and the dopamine > receptors involved in movement disorders are slightly different than > those involved in schizophrenia. In schizophrenia the holy grail is to > find a drug which acts exclusively on the receptors involved in > cognition and avoid action on those involved in movement disorders. > > I hope this helps. > > Charlie > -- > ********************************************************** > CHARLES T. MEYER, M.D. > MADISON, WISCONSIN > [log in to unmask] > ********************************************************* Charles The question of Marge is not fully answered, I think The question is not about PWP's having schizophrenia or vice versa, but about the phenomenon that the l-dopa used by PWP's can cause some symptoms that are similar to some symptoms of schizophrenia (hallucinations and confusion)and vice versa psycholeptica indicated for schizophrenia can not cause PD, but symptoms who are like PD symptoms: bradykinesia, dyskinesia. Does it make sense to say that the med's for both diseases don't arrrive only in the disturbed place of the brain, but unfortunately as much in undisturbed places. The l-dopa used by PWP's causes to high a level of dopamine in the "schiz part" of the brain giving "schiz." symptoms. The psycholeptica arriving unfortunately in the extra-pyramidal system too, causing in that region a shortage of dopamine and hence Parkinson like symptoms. The question now is whether this symmetry is in any way indicative of a relationship between these diseases. I asked myself something else. Some time ago PWP's suffering from light intolerance was a topic on the list. Can this be caused by to a high level of dopamine in the retina. Ida Kamphuis, Holland.