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Brain and Joy - In regard to sleeplessness and Eldepryl: an informal poll of our support group a year ago revealed that at least half of the members had stopped taking Eldepryl because of sleeplessness. Some, like my husband, had cut down to one first thing in the morning. Eventually my husband stopped taking it altogether, reasoning that he'd had a couple of years of its protective effects, and that was better than nothing, but that being able to sleep at night was even better yet. (Wish I could report that now he sleeps like a baby, but alas . . . ). Margie