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------------4544651D15440 Content-Transfer-Encoding: 7bit Content-Type: text/plain; charset=us-ascii Hi Camille, Welcome to the list. There is convincing evidence that Schizophrenia runs in families. That is to say I am morer likely to have a schizophrenic episode if a member of my family is schizophrenic- the closer the relative (biologically) the higher the likelihood. There appears not to be any evidence- to my knowledge- that one is more likely to become schizophrenic if the disease is on one side or the other of the family tree(mother or fathers side). Regarding PD, the evidence is much more confusing. There are undoubtedly some families in which PD is inheritted. There has recently been data showing that a particular gene or group of genes is responsible for PD. If this is true then PD I would assume is an inheritted disease - or at least a vulnerability to the disease coupled with an environmental agent such as a virus or toxin is inheritted-. I am not aware of studies of both diseases in the same family but I suspect that there is not a relationship for the reason that I mentioned in my last posting- that pathogenesis of schizophrenia is almost certainly more than an excess of dopamine. I hope I haven't confused the picture more. Again welcome to the list. Charlie -- ********************************************************** CHARLES T. MEYER, M.D. MADISON, WISCONSIN [log in to unmask] ********************************************************** ------------4544651D15440 Content-Transfer-Encoding: 7bit Content-Type: text/html; charset=us-ascii <HTML><BODY> <DT>Hi Camille,</DT> <DT> </DT> <DT>Welcome to the list. There is convincing evidence that Schizophrenia runs in families. That is to say I am morer likely to have a schizophrenic episode if a member of my family is schizophrenic- the closer the relative (biologically) the higher the likelihood. There appears not to be any evidence- to my knowledge- that one is more likely to become schizophrenic if the disease is on one side or the other of the family tree(mother or fathers side). </DT> <DT> </DT> <DT>Regarding PD, the evidence is much more confusing. There are undoubtedly some families in which PD is inheritted. There has recently been data showing that a particular gene or group of genes is responsible for PD. If this is true then PD I would assume is an inheritted disease - or at least a vulnerability to the disease coupled with an environmental agent such as a virus or toxin is inheritted-. </DT> <DT> </DT> <DT>I am not aware of studies of both diseases in the same family but I suspect that there is not a relationship for the reason that I mentioned in my last posting- that pathogenesis of schizophrenia is almost certainly more than an excess of dopamine.</DT> <DT> </DT> <DT>I hope I haven't confused the picture more.</DT> <DT> </DT> <DT>Again welcome to the list.</DT> <DT> </DT> <DT>Charlie<BR> -- <BR> **********************************************************<BR> CHARLES T. MEYER, M.D.<BR> MADISON, WISCONSIN<BR> [log in to unmask]<BR> **********************************************************<BR> </DT> </BODY> </HTML> ------------4544651D15440--