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On Sun 19 Jan, Joao Paulo Carvalho wrote:
> Hello Nigel,
>
> Rosemary J Oram wrote:
> >
> > Answer to Joao Paulo Carvalho
> >
> > 1. Madopar Tablets each contain 200mm. They are grooved in four parts for
> > ease of division.
> >
> > Madopar capsules contain 100mm. + 25mm Benserazide. These are slow
> > release capsules.
> >
> > 2. My present medication is
> >
> >                 7 a.m.         2 Madopar capsules
> >                                         1 x half Madopar tablet.
> >
> >                                         1 permax tablet
> >                 11 a.m.         Ditto
> >                 4 p.m.         Ditto
> >                 9.30 p.m.       2 Madopar capsules
> >                                         1xhalf Madopar tablet
> >                                         [No permax]
> > Nigel Oram ([log in to unmask])
>
> If I undestood correctly :
>
> 1. Madepar capsules do NOT have bensenrazide.They are pure levodpa.
>
> 2. You take daily about 1000 mg of levodopa.Is'nt too much ?
>
>
> Here in Brazil it is found a med under the name of Prolopa250(200 mg of
> levvodopa + 50 mg of bessenrazide) in tablets.There are'nt tablets of
> pure levodopa.
>
> Best wishes,
>
>    +----| Joao Paulo de Carvalho   |------ +
>    |         [log in to unmask]     |
>    +--------| Salvador-Bahia-Brazil |------+
>
>
Let's see now:
1) I guessed that Nigel's tablets were Madopar 125s because the 200 mg
tablet seemed too big.

2) I was partly right: Nigel takes 100 mg doses but does it by breaking
a 200 mg tablet in half.  Why do you do that ?  Is it a cost benefit?
One of the reasons why I use Madopar Dispersibles containing only 50 mg
of Levodopa (And they are grooved to split in half) is that I can break
the tablet in 2 easily, and then in half again, giving me effectively a
'resolution'  of 12.5 mg per piece of tablet. Starting with 200 mg and
breaking that down  seems to be doing it the hard way. ( Keep the
golden rule in mind : A little and often is better than an occasional
large dose.

If I have counted up correctly that ;puts you on a total 1200 mg per day
which is a fairly normal dosage. You appear to be just starting Permax,
and I would expect that your doctor would leave the Madopar at the
present level, and gradually raise the Permax, as your need increases.

Joao Paulo: I don't think anyone takes pure levodopa these days: The 99%
which fails to get to the brain can make you very ill. Certainly if you
say Madopar or Sinemet, you are talking about a 'buffered' tablet. i.e.
one in which the levodopa is protected from attack while it is in the
bloodstream by Carbidopa (in Sinemet) or Benserazide in Madopar.

Are we all straight now ?

Regards,
--
Brian Collins  <[log in to unmask]>