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A request to NADH users: Please try to add to the NADH survey I posted yesterday. I spoke to Dr.Georg Birkmayer of Vienna, the developer of ENADA-brand NADH, this morning. NADH is the co-factor for the enzyme, tyrosine hydroxylase, in the normal chemical production of human dopamine in the substantia nigra .Birkmayer said that among his 885 PWP's in his VIenna study, NADH allowed marked improvement in at least 1/3 of the test group, even after 3 years of NADH use. He also mentioned the research work at the Univ. of Paris on another study NADH users. ENADA from Menuco, in 5.0 mg doses, apparently takes 4 hours to work, but lasts 4 hours, once it kicks in. Apparently, MARKED REDUCT IONS IN SINEMET USE BECOME POSSIBLE IN MANY CASES. I will be trying two different daily dosing patterns and comparing them: 2 x 5.0 mg./day, about 1/2 hour before breakfast and again, 1/2 hour before lunch, or, 3 x 5.0 mg./day, adding a third evening dose, again 1/2 hour before eating an evening meal. Ivan Suzman 47/10 Portland, Maine snowless winter / land of lighthouses and woodstoves/sunny and 45 F.