Jacquie, I personally am currently taking 25 mg/day currently. I ran into some trouble several years ago when I reached 30> I was seeing Harold Klawans at the time and he told me he sometimes used doses > 50mg/day and if I recall he said that he had heard of doses up to 100mg/day but don't quote me on that. It was several years ago that we discussed it. -- ********************************************************** CHARLES T. MEYER, M.D. Superbowl prediction from the land of MADISON, WISCONSIN Cheese and bratwurst [log in to unmask] Packers 35 Patriots 10 GO PACKERS **********************************************************