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On 20 Jan 1997 Henry Guttentag wrote: >SHE SHOULD BE ON SINAMET HOWEVER SHE CLAIMS TO HAVE SIDE EFFECTS FROM >THE MEDICATION,SO THE DOCTOR HAS KEPT HER ON ARTANE?? >MEDS SHE TAKES: >ARTANE, EFFEXOR, ATIVAN,VICODIN, LODINE, RISPERDAL AND PANCREAS Henry, A search in the Clinical Pharmacology program yielded the following: Current 7 medications: =9AAcetaminophen; Hydrocodone (Anexsia=AE, Anodynos=AE DHC, Hy-Phen=AE, L= orcet=AE, Lortab=AE, Vicodin=AE)* =9AEtodolac (Lodine=AE) =9ALorazepam (Ativan=AE) =9APancrelipase (Cotazym=AE, Ilozyme=AE, Pancrease=AE, Viokase=AE) =9ARisperidone (Risperdal=AE) =9ATrihexyphenidyl (Artane=AE) =9AVenlafaxine (Effexor=AE) Drug Interactions Report *New drugs, common drugs, less common drugs, and/or nutritional products are indicated by asterisks. The information available for these drugs is less thorough than for the others, so you may wish to consult other references. Lorazepam/Acetaminophen; Hydrocodone Concomitant administration of lorazepam with CNS-depressant drugs, including opiate agonists, phenothiazines, barbiturates, ethanol, H=C0-blockers, general anesthetics, and tricyclic antidepressants, can potentiate the CNS effects (i.e., increased sedation or respiratory depression) of either agent. Trihexyphenidyl/Lorazepam Ethanol and other CNS depressants, such as anxiolytics, sedatives, and hypnotics, can increase the sedative effects of trihexyphenidyl. Additive Adverse Reactions Report *New drugs, common drugs, less common drugs, and/or nutritional products are indicated by asterisks. Since no adverse reaction information is available for these drugs, this report does not reflect their contribution to the adverse reaction spectrum. 4 of these drugs may cause: -constipation (etodolac; risperidone; trihexyphenidyl; venlafaxine) -dizziness (etodolac; lorazepam; risperidone; venlafaxine) -nausea/vomiting (etodolac; pancrelipase; risperidone; venlafaxine) 3 of these drugs may cause: -abdominal pain (etodolac; pancrelipase; risperidone) -anxiety (risperidone; trihexyphenidyl; venlafaxine) -blurred vision (risperidone; trihexyphenidyl; venlafaxine) -drowsiness (lorazepam; risperidone; venlafaxine) -libido decrease (lorazepam; risperidone; venlafaxine) -withdrawal (lorazepam; risperidone; venlafaxine) 2 of these drugs may cause: -agitation (risperidone; trihexyphenidyl) -ejaculation dysfunction (risperidone; venlafaxine) -fatigue (lorazepam; risperidone) -headache (lorazepam; risperidone) -impotence (risperidone; venlafaxine) -insomnia (risperidone; venlafaxine) -maculopapular rash (etodolac; pancrelipase) -syncope (lorazepam; risperidone) -tremor (lorazepam; venlafaxine) -xerostomia (trihexyphenidyl; venlafaxine) Drugs/Contraindications Warning -New drugs, combination drugs, less common drugs, and/or nutritional products are indicated by asterisks. Since no contraindications information is available for these drugs, this report may not contain all possible precautions. Precaution: Risperidone in Parkinson's disease Risperidone should be used with caution in patients with Parkinson's disease because of possible development of extrapyramidal symptoms. Therapeutic Duplication Alert No duplicate therapy was identified. ---------- Perhaps armed with all the information you are gathering from the list and also following Brbara Mallut's wise counsel to pursue a discussion with your wife, you could present your well founded concerns to the neurologist. There are too many variables to sort through without rhe neurodoc's input. Best to you both, Margaret Tuchman (55yrs,Dx 1980) NJ-08540 [log in to unmask]