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Hello Marty Rose, Marty Rose wrote: > > I have recently (this week) started a more vigorous excercise routine. > I have been pretty inactive since summer. My questions concern Sinemet > requirements whe exercising. I am noticing that it wears off sooner > than normal. Do we need to increase the dosage when exercising and by > how much? Thanks for any feed back you might give me. > > Marty Rose 56/PD 9 years I practice competitive sport because I love them(soccer) and it seems to me that the brain barrier lets the absorption of levodopa to be more easy(permeable).I suppose that is the stress that liberates adrenaline and serotinine caused by the game which contributes to this. In your exercise there may be no such liberation of these substances since you are not under the competition stimulation,and so yours results seems to be just the other way around. Of course these are pure supositions from the litle old me.(During the war in Iraque soldiers under stress seems to had a higher absorption of chemical products than what was expected from tests done with people under normal circunstances). Best wishes, +----| Joao Paulo de Carvalho |------ + | [log in to unmask] | +--------| Salvador-Bahia-Brazil |------+