This is a follow-up to an earlier post (then unconfirmed) about the possible role of melatonin and ovarian cancer. I am still trying to obtain more information on this subject. Best, Bob ------- Forwarded Message Follows ------- Date: Tue, 28 Jan 1997 21:14:14 +1100 (EST) From: John Savage <[log in to unmask]> Bcc: Subject: Re: melatonin -> ovarian cancer On sci.med I posted: >Australian government health authorities have issued a public warning >that they believe melatonin can cause ovarian cancer. I'll post again if I can find out more details of that warning. Meanwhile, here's an extract from a Letter to the Editor (SMH, Jan 20,'97): I'm concerned that NSW appears to permit the unregulated sale of the hormone melatonin in doses with would result in blood levels far above the normal. [...] Melatonin is a moderator of other hormones, especially in sexual organ functions. [...] unusual fluctuations in these hormones are associated with cancerous changes in reproductive organs. It was not surprising then to find, during research into melatonin for my PhD, that the most published investigations in this area found, in a study of mammals, that chronic administration of melatonin to young adult females did not retard aging but resulted in early death owing to development of a high incidence of tumors, primarily in the re- productive tract. [...] Low-risk doses of melatonin may be available by prescription in the future. For now, however, people might be better-advised to exercise, relax, and follow recommended diets. Mary MacGibbon, Clovelly. *********************************** ROBERT A. FINK, M. D., F.A.C.S. Neurological Surgery 2500 Milvia Street Suite 222 Berkeley, CA 94704-2636 USA Phone: (510) 849-2555 FAX: (510) 849-2557 WWW: <http://www.dovecom.com/rafink/> "Ex Tristitia Virtus" ***********************************