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I have a CO generated Parkinson's syndrome, and, as I understand it, P.S. is like any other syndrome, eg. carpel tunnel, Down's, in that being taken away from the offending agent, the sufferer is not supposed to degenerate/worsen. I'm not sure if this is exactly the case, but I have had PS for 8 and a half years now, with no sign of degeneration...and no added meds. Jacob Drollinger