I am 62, female, and have had Parkinson Disease for 17 years. I have taken Sinemet for 8 or 9 years, Was recently switched to Sinemet CR {50/200} . My pill popping consists of Sinemet CR {4 times a day}, 7.2 mg of Parlodel 3 times a day. Sinemet 25/l00 when needed not to exceed 2 or 3 a day - middl;e of the night dosage for sleep. I also take 100 mg Pa melor at bedtime. Edie Luther [log in to unmask]