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The recent series of letters about breathing and P.D. prompts me to repeat a message I sent some time ago. There were no reactions at that time. My wife, Doris (73,4) has been taking oxygen because of a worsening congenital pulmonary arteriovenous malformation. This defect has been getting worse and next week she will have an intervention to seal it off. The consequence of her taking oxygen has been remarkable for her Parkinson symptoms. Her insomnia, which has plagued her terribly, has been sharply reduced. Her restless legs have almost disappeared. She has been maintaining her sinemet regimen and ativan. As part of her insomnia problem she had a sleep test and the neurologist reported that her restless legs subsided when he increased her oxygen input. Has anyone been taking oxygen for other conditions and found that it affected their parkinson symptoms. Her pulmonary shunt has meant that a considerable percentage of her blood had not been oxygenated. My suspicion is that this increase in "toxicity" in her blood would be comparable to the many cases of environmental toxicity that others have reported. However her cardiologist and neurologist think that her pulmonary vascular problems are totall unrelated to her parkisons. I am not convinced. Jules