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My PD friend was diagnosed about 2 yrs. ago and is only taking Eldepryl. He is seeing a neurologist on a regular basis and has been doing very well up to now. Just lately he has been complaining that his dress shoes are not comfortable anymore and that his big toe is cold and numb. He is thinking it may be Reynaud's Syndrome and I am thinking that the PD is speeding up. Does anyone have any thoughts or information or personal experience with a problem such as this? Thanks for your help. Maggie Salls Newport News, VA