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. Just lately he has been complaining that his dress shoes are > not comfortable anymore and that his big toe is cold and numb. He is > thinking it may be Reynaud's Syndrome and I am thinking that the PD is > speeding up. > Maggie Salls Your friend should check with his doctor concerning this foot problem. If his big toe is *cold* and numb there is a possibility that it is, indeed, a circulatory problem. I'm not familiar with PD acting in this fashion - but I've seen more than a few folks with arterial spasm or occlusion who voice that complaint. ------ Mary Ann