Sue: You don't mention the dosages given your mother. In the beginning the Sinemet dosages should be small then gradually incremented to adjust to adequate dosage. How much depends on the individual. But many people have 'reactions' to Sinemet in the beginning. Also dyskinesia (agitated movements of the head and other extremities) can be a result of too much Sinemet. Depending on the dosage and your mother's condition you may be seeing dyskensia. Usually all unusual activity will cease when the patient sleeps. There may be some occasional leg movement if the patient tends to have Restless Leg Syndrome (RLS). I'm not a physician but with 20 years as a caregiver for my wife (58 years of age) we have been through most of the ropes. I will relay some of the information we have accummulated over the years if it will be of help to you. I would anticipate you are seeing your mother react to the doubling of the medication (Sinemet) which may settle down in a few days. My reaction to doubling the meds is.......too much, too quickly. Better to increase gradually until dyskensia is noticed then back away slightly. If I can help let me know ........Jack *********************************************************** E. Jack Savely [log in to unmask] Topeka, Kansas CG - Jeannette 58 - 20 Starliter on Chat *********************************************************** KANSAS - 'THE WHEAT STATE' HOME OF THE SUNFLOWER AND 'TOTO' Ad Astra per Aspera - 'To the Stars through Difficulty' ***********************************************************