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Hi All I hope this comment doesn't start a war of words but I would like to point out that all you guys who are saying "SINEMET BEFORE MEALS --ALWAYS" have forgotten the First Law of Parkinsons. <Every PWP is unique in symptoms and drug response and what works for one PWP may not work for another> Some PWP are more likely to be affected by nausea than other PWP and it may take a few years to adjust to levodopa before breakfast. Try it both ways and then do what's best for you. Anne Rutherford <[log in to unmask]>