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Mary,

I cannot locate Brian's question, but I came full face with half life of
Valium when my dad with PD was overdosed by a cardiologist and
anesthesiologist when he had a pacemaker replaced.  Valium has an
extremely long half-life and indeed he was in a coma for two months
after several large IV doses given.  His neurologist did not expect a
good prognosis, but he did eventually recover.  I think that the
half-life does relate to the length of effect of the drug.

Aloha, Gail
--
Gail B. Post, RN,MS,CSN
Maryknoll Schools
Honolulu, HI 96822