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Dear Ivan: Your theory is as good as anybody's since we still do not know what causes PD. My wife has PD and we have a son with diabetes. My wife's mother is also diabetic. Thought you might be interested. Henry Guttentag CG for wife 62/8 _______________________________________________ Ivan M Suzman wrote: > > Dear Listmembers, > > Late night thoughts from the coast of Portland, Maine...CONT. from > March,'96.... > > The onset of my PD was at age 37. My older brother has been diabetic > since the age of 16 (I'm now 47 and he is 51). > > 1) Are there others out there who are young onset PWP's with young > onset diabetes in a relative? > > 2) Whether YOPD or not, do you have a diabetic relative, alive or > deceased? > > I have a genetic theory: a gene that regulates adrenaline's > manufacture is involved in BOTH PD AND DIABETES. Dopamine eventually > breaks down to adrenaline, and adrenaline controls insulin levels > (inhibits it). So THE SAME GENE COULD CAUSE BOTH PARKINSON'S (by > interrupting normal dopamine supply) AND/OR DIABETES (the lost dopamine > causes changed adrenaline levels, which in turn, causes insulin supply > problems). > > Incidnentally, of 61 Maine PWP' s I have talked to, 43 have/had a > diabetic relative. I THINK I COULD BE ON TO SOMETHING. > > What's going on here, gang?? > > Ivan Suzman > 47/10 Portland, Maine > land of lighthouses