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Just a note to thank those of you who very helpfully, and rapidly (PD?) responded to my question about Artane substitutions. I do appreciate this very much. Another topic: I would like to know definatively when pramipexole is going to be on the market. Is the best route through the FDA or Kaiser or suggestions please? There must be many of us who would like to know the status of this drug; I suspect it takes a while for info to filter down to neurologists. Barbara. B.C. Canada Barbara Hodson 50/6 British Columbia