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Yourfirstname Yourlastname wrote: > > Does B6 interfere with Sinemet? I read in Good Nutrition in Parkinson's > Disease put out by the APDA that, "B6 does not worsen PD if used in the > recommended amount of 2 mg. per day. If supplemental vitamins are used, > intake should not exceed 5 mg. B6-free multivitamins are only needed if a > person is taking levadopa rather than Sinemet." (p.14) Has anyone heard the > contrary? Thank you for any response! > Michelle, I believe this is correct. Originally, only levodopa was available. B6 lessened the drug's effect, and it was recommended to take only the RDA of 2 mg/daily. The combination of levodopa/carbidopa in Sinemet is much better. Carbidopa prevents the negative B6 effect. However, I doubt that megadoses of B6 would be advisable. 5 mg daily should be fine. Best regards, Kathrynne -- Kathrynne Holden, MS, RD Editor-in-Chief, "Spotlight on Food--nutrition news for people 60-plus" Tel: 970-493-6532 Fax: 970-493-6538 http://www.fortnet.org/~fivstar You may wish to contact: Better Business Bureau of the Mountain States, < [log in to unmask]> for further information.